MTHF Plus B12 features Quatrefolic® and MecobalActive™ in great-tasting, quick-dissolve tablet form. Quatrefolic is the glucosamine salt of 5-MTHF—the most biologically active form of folate that increases plasma folate more effectively than folic acid. MecobalActive is a patented, highly pure form of methylcobalamin—body-ready B12.*